In the last 61 years, Australian Centre for Microscopy & Microanalysis (ACMM, formerly EMU) has been providing excellent research support, service and training to the researchers in University of Sydney and research institutes across Australia, as well as outreaching to communities and industries. The expertise extends from specimen preparation, data acquisition and data analysis, and applications across multiple disciplines, from archaeology and zoology to chemistry, engineering and physics.
The light and optical section in ACMM has expanded from Madsen Building to three buildings including Madsen, Charles Perkins Centre and Brain and Mind Centre in the Camperdown Campus. Equipped with over 27 light and laser microscopes, we could explore physical and biological structures from micro to nano scales from two-dimension (xy) to five-dimension (xyztλ).
We are capable to explore sub-cellular structure using super resolution microscopy based on GSD (Ground State Depletion) and STED (STimulated Emission Depletion) technology, over the diffraction limit, up to 20nm and 50nm in resolution, respectively.
We are capable to explore deep into tissue utilising the multiphoton and DIVE(Deep In Vivo Explorer) microscope, in the application of intravital or deep tissue imaging. Images of chemical-cleared tissue can be captured up to 2.5mm in depth.
The availability of advanced EMCCD and sCMOS cameras in ACMM expands the research capability including high-speed high-sensitivity TIRF (Total internal reflection fluorescence) microscopy, and other experiments such as calcium imaging and bioluminescence imaging.
The development of core research facility on microscopy and microanalysis continues providing our researchers with the state-of-the-art infrastructure and technical support to pursue research excellence.